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  1. First/Co-first/Corresponding Author Publications

    • Yan Y, Martinez R, Rasheed MN, Cahal J, et. al.. Germline and somatic mutations in the pathology of pineal cyst: A whole-exome sequencing study of 93 individuals. Molecular Genetics & Genomic Medicine 2021 May 4:e1691.

    • Yan Y, Takayasu T, Hines G, Dono A, et. al.. Landscape of Genomic Alterations in IDH Wild-Type Glioblastoma Identifies PI3K as a Favorable Prognostic Factor. JCO Precision Oncology 2020 4:575-584. jcopo

    • Yan Y, Sun N, Wang H, Kobayashi M, et. al.. Whole genome-derived tiled peptide arrays detect pre-diagnostic autoantibody signatures in non-small cell lung cancer. Cancer Research. 2019 Apr 1; 79(7):1549-1557. CAN

    • Morita K*, Kantarjian HM*, Wang F*, Yan Y*, Bueso-Ramos C, et. al.. Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia. Journal of Clinical Oncology. 2018 Jun 20;36(18):1788-1797. (*Co-first Authors) jco

    • Nguyen K*, Yan Y*, Yuan B, Dasgupta A, et. al.. ST8SIA1 regulates tumor growth and metastasis in TNBC by activating the FAK-AKT-mTOR signaling pathway. Molecular Cancer Therapeutics. 2018 Dec;17(12):2689-2701. (*Co-first Authors

    • Takahashi K*, Hu B*, Wang F*, Yan Y*, Kim E, et. al.. Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide. Blood. 2018 Apr 19;131(16):1820-1832. (*Co-first Authors)

    • Beli E*, Yan Y*, Moldovan L, Vieira CP, et. al.. Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes. 2018 Sep;67(9):1867-1879. (*Co-first Authors)

    • Yan Y, Gao R, Trinh TLP, Grant MB. Immunodeficiency in Pancreatic Adenocarcinoma with Diabetes Revealed by Comparative Genomics. Clinical Cancer Research. 2017 Oct 15;23(20):6363-6373.

    • Yan Y, Salazar T, Dominguez JM 2nd, et. al.. Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes. PloS ONE. 2013 Nov 7;8(11): e80029.

    • Yan Y, Li SW, Yang CY, Luo W, et. al.. The prediction of a common neutralizing epitope of H5N1 Avian Influenza Virus by in silico Molecular Docking. Chinese Science Bulletin. 2008 53(6): 868-877.

  2. Selected Co-author Publications

    • Wang F*, Morita K*, DiNardo CD, Furudate K, Tanaka T, Yan Y, Patel KP, Macbeth KJ, Wu B, et. al.. Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia. Nature Communications 2021 May 10;12(1):2607.

    • Morita K*, Wang F*, Jahn K*, Hu T, Tanaka T, Sasaki Y, Kuipers J, Loghavi S, Wang SA, Yan Y, et. al.. Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics. Nature Communications 2020 Oct21;11(1):5327.

    • Kaur B, Hong B, Chapa V, Saini U, Modgil P, Cohn DE, He G, Siddik ZH, Sood AK, Yan Y, et. al.. Oncolytic HSV Therapy Modulates Vesicular Trafficking Inducing Cisplatin Sensitivity and Anti-tumor Immunity. Clinical Cancer Research. 2020 Oct 21.

    • Dienel A, Ammassam Veettil R, Hong SH, Matsumura K, T PK, Yan Y, et. al.. Microthrombi Correlates With Infarction and Delayed Neurological Deficits After Subarachnoid Hemorrhage in Mice. Stroke 2020 Jul;51(7):2249-2254

    • Peng H*, Pan S*, Yan Y, Brand R, et. al.. Systemic proteome alterations linked to early stage pancreatic cancer in diabetic patients. Cancers (Basel). 2020 Jun 11;12(6):1534.

    • Otani Y, Yoo JY, Chao S, Liu J, Ramirez AC, Lee TJ, Hurwitz B, Yan Y, et. al.. Oncolytic HSV infected glioma cells activate NOTCH in adjacent tumor cells sensitizing tumors to gamma secretase inhibition. Clinical Cancer Research. 2020 May 15;26(10):2381-2392

    • Chekouo T, Stingo FC, Class C, Yan Y, et. al.. Investigating Protein Patterns in Human Leukemia Cell Line Experiments: A Bayesian Approach for Extremely Small Sample Sizes. Statistical Methods in Medical Research. 2020 Apr;29(4):1181-1196

    • Hsu JI, Dayaram T, Tovy A, Braekeleer ED, Jeong M, Wang F, Zhang JH, Heffernan T, Sonal F, Kovacs J, Marszalek J, Bristow C, Yan Y, et. al.. Cytotoxis chemotherapies create a fitness landscape that favors clonal hematopoiesis of PPM1D mutants. Cell Stem Cell. 2018 Nov 1;23(5):700-713.

    • Takahashi K*, Wang F*, Morita K, Yan Y, Hu P, et. al.. Integrative genomic analysis of adult mixed phenotype acute leukemia (MPAL) delineates lineage associated molecular subtypes. Nature Communications. 2018 Jul 10;9(1):2670.

    • Bhatwadekar A, Yan Y, Stepps V, Hazra S, et. al.. miR-92a Corrects CD34+ Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation. Diabetes. 2015 Dec;64(12):4226-37.

    • Chen S, Ibrahim N, Yan Y, Wong S, Wang H, Wong F. Risk Stratification in Patients with Advanced-stage Breast Cancer by Pretreatment 18F-FDG PET/CT. Cancer. 2015 Nov 15;121(22):3965-74.

    • Bhatwadekar A, Yan Y, Qi X, Thinschmidt JS, et. al.. Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow. Diabetes. 2013 Jan;62(1):273-82.

    • Hazra S, Rasheed A, Bhatwadekar A, Wang X, Shaw LC, Patel M, Caballero S, Magomedova L, Solis N, Yan Y, et. al.. Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes. Diabetes. 2012 Dec;61(12):3270-9.